私がかねてから述べてきた点が動物実験によって証明された。
接触感染ルートよりも、エアロゾル感染ルートの方が重症化する。
お気をつけ下さい。手洗いサボっても換気忘れるな、です。
エアロゾール、マイクロ飛沫で感染したほうが、接触感染した場合より重症化する可能性が実験で分かりました https://t.co/bAMan5I2nQ
— DNAパパ👨🏻🔬ゲノム🧬解析サイエンティスト 🇦🇺永住17年目 (@DNA_PAPA) December 31, 2020
1/📌NIH Study: COVID-19 severity could depend on route of infection: Infection through inhaling #Airborne virus could lead to more severe disease than infection from fomites (contact w/ contaminated objects.) To test it, hamsters were infected via the different routes. 1/7🧵 pic.twitter.com/9lX7sMrKUG
— Dr. Ali Nouri (@AliNouriPhD) December 29, 2020
3/Also, compared to intranasal exposure, aerosol exposed
— Dr. Ali Nouri (@AliNouriPhD) December 29, 2020
hamsters had higher viral load in trachea and lung "suggesting aerosol exposure more efficiently deposits viral droplet nuclei in the lower respiratory system" Preprint: 3/7https://t.co/gCpBCsvRuj
5/In contrast to other mode of transmission where virus hits nasal cavity and finds its way into lungs, aerosols can directly reach alveolar region and attack alveolar cells that produce Pulmonary Surfactant. PS is needed to lower surface tension & prevent alveoli collapse. 5/7 pic.twitter.com/PrYSZJNJgh
— Dr. Ali Nouri (@AliNouriPhD) December 29, 2020
7/Viewing transmission through the lens of bioaerosol mechanics highlights the need for mitigation approaches such as ventilation and other measures, and new therapeutic interventions, like surfactant therapy to alleviate ARDS symptoms. 7/7https://t.co/GLjdk9gkZU
— Dr. Ali Nouri (@AliNouriPhD) December 29, 2020