7410. Science 論文

読んで、よかった。

Science  27 May 2020:
eabc6197
DOI: 10.1126/science.abc6197

最後のところ、感動的だった。

Aerosol transmission of viruses must be acknowledged as a key factor leading to the spread of infectious respiratory diseases. Evidence suggests that SARS-CoV-2 is silently spreading in aerosols exhaled by highly contagious infected individuals with no symptoms. Owing to their smaller size, aerosols may lead to higher severity of COVID-19 because virus-containing aerosols penetrate more deeply into the lungs (10). It is essential that control measures be introduced to reduce aerosol transmission. A multidisciplinary approach is needed to address a wide range of factors that lead to the production and airborne transmission of respiratory viruses, including the minimum virus titer required to cause COVID-19; viral load emitted as a function of droplet size before, during, and after infection; viability of the virus indoors and outdoors; mechanisms of transmission; airborne concentrations; and spatial patterns. More studies of the filtering efficiency of different types of masks are also needed. COVID-19 has inspired research that is already leading to a better understanding of the importance of airborne transmission of respiratory disease.

様々なエビデンスから、無症状の人から稀に高いタイターのウイルスがエアロゾルとして「静かに」撒き散らされていると示唆されている。小さいサイズのエアロゾルは、COVID-19の重症化に関与する。なぜなら、ウイルスを含むエアロゾルは肺のより奥にまで到達するからだ Environ. Int. 141, 105794 (2020). doi:10.1016/j.envint.2020.105794pmid:32416374

と書いてある。

COVID-19の成立に必要なウイルス量や、発症前、発症後にどんな量のウイルスを排出しているか、まだ誰も知らない。

これがmultidisciplinary=学際的な態度だと思うの。

新しいウイルスなんだから、もっと謙虚に恐れ、安全マージンは広く取りたいと私は思うのです。